An efficient method to enhance recovery and detection of SARS-CoV-2 RNA in wastewaterArticle Published on 2023-08-012023-07-11 Journal: Journal of environmental sciences (China) [Category] COVID19(2023년), [키워드] environmental monitoring Pathogens Surveillance Viral RNA virus Wastewater. [DOI] 10.1016/j.jes.2022.10.006 PMC 바로가기
Long-term passive wastewater surveillance of SARS-CoV-2 for seven university dormitories in comparison to municipal surveillanceArticle Published on 2022-12-152022-11-15 Journal: The Science of the total environment [Category] COVID19(2023년), SARS, 치료기술, [키워드] addition chain collected Community COVID-19 effective eight Frame Frequency increases in Passive Passive sampling peaked plant Quantitative rates of infection reaction RT-qPCR SARS-CoV-2 SARS-CoV-2 detection SARS-CoV-2 transmission Seven similarity spread of COVID-19 Surveillance Treatment university University residences Viral load Viral RNA was done wastewater Wastewater-based surveillance (WBS). [DOI] 10.1016/j.scitotenv.2022.158421 PMC 바로가기
Reverse transcriptase-free detection of viral RNA using Hemo Klentaq DNA polymeraseArticle Published on 2022-12-152022-11-15 Journal: Analytical biochemistry [Category] COVID19(2023년), SARS, 치료기술, 치료제, [키워드] affected amplification Analysis can be used caused comparable COVID-19 Degraded RNA demonstrated determine DNA polymerase Efficiency freeze-thaw cycles limitations Nasopharyngeal swab Nearby Nearby primers overcome pandemic patients PCR polymerase chain polymerase chain reaction Primers provide provided reliability reverse transcriptase Reverse transcriptase activity reverse transcription RNA RT-PCR SARS-CoV-2 SARS-CoV-2 detection target transcriptase Viral RNA Viral RNA. [DOI] 10.1016/j.ab.2022.114960 PMC 바로가기
Examples of Structural Motifs in Viral Genomes and Approaches for RNA Structure CharacterizationReview Published on 2022-12-142023-07-11 Journal: International Journal of Molecular Sciences [Category] COVID19(2023년), [키워드] cryo-EM high-throughput methods secondary and tertiary structures structure prediction Viral RNA viruses. [DOI] 10.3390/ijms232415917 PMC 바로가기 [Article Type] Review
New-onset dermatomyositis following SARS-CoV-2 infection and vaccination: a case-based reviewArticle Published on 2022-12-012022-11-15 Journal: Rheumatology International [Category] COVID19(2023년), SARS, 진단, 치료기술, [키워드] Affect antibodies antibody association autoantibody Autoimmune disease COVID-19 COVID-19 vaccines Defense dermatomyositis Immunosuppressive treatment increase in Infection Intensive Interaction internal organ MDA5 mRNA vaccines occurred pandemic Patient patients positive pulmonary system reported required SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2. Seven systematic review the SARS-CoV-2 type I vaccination Viral RNA [DOI] 10.1007/s00296-022-05176-3 PMC 바로가기
Molecular detection of SARS-COV-2 in exhaled breath at the point-of-needArticle Published on 2022-12-012022-11-15 Journal: Biosensors & bioelectronics [Category] COVID19(2023년), SARS, 진단, 치료기술, [키워드] Aerosols Analysis Antigen approach approach breath contagious contagiousness detect diagnostics Direct equipment help identify impactor Infection Lab-on-a-chip less limitation molecular Nasopharyngeal swab offer Particle Pathogens patients PCR positive quantification respiratory infections RT-qPCR Saliva SARS-CoV-2 SARS-CoV-2 pandemic SARS-CoV-2. Spread subject temporal dynamics tested Viral load Viral RNA viral shedding Volume while [DOI] 10.1016/j.bios.2022.114663 PMC 바로가기
Building-level wastewater surveillance of SARS-CoV-2 is associated with transmission and variant trends in a university settingArticle Published on 2022-12-012022-11-16 Journal: Environmental research [Category] COVID19(2023년), SARS, 변종, [키워드] Alpha variant analyzed associations Building-level surveillance Clinical data clinical testing collected complement Concentration contributed COVID-19 COVID-19 case creating Epidemiology genetic mutation hotspot identify include indicate Intervention Isolation less log N1 and N2 Nucleocapsid gene positive positive control quantification quarantine repeated reported Research SARS-CoV-2 SARS-CoV-2 RNA second wave South spring statistical significance statistically significant Surveillance Transmission university variant variants of concern Viral RNA Viral transmission VOCs Wastewater-based epidemiology. [DOI] 10.1016/j.envres.2022.114277 PMC 바로가기
Identification and characterization of the anti-SARS-CoV-2 activity of cationic amphiphilic steroidal compounds양이온성 양친매성 스테로이드 화합물의 항 SARS-CoV-2 활성의 확인 및 특성화Article Published on 2022-12-012022-09-11 Journal: Virulence [Category] COVID19(2023년), SARS, 변종, 유전자 메커니즘, 치료제, [키워드] aggravation ameliorated anti-SARS-CoV-2 activities Anti-SARS-CoV-2 Activity Antiviral antiviral activity cationic caused cell lines characterization cholesterol complex Compound compounds COVID-19 pandemic COVID-19 patient cytopathic Cytopathic effect Drug discovery effective envelope envelope proteins epiandrosterone followed by hACE2 HEK293 host cell host cells identification in vitro in vivo indicated inhibited initial involved life Lipid mechanism membrane modulate modulation Mortality Pathogenesis progeny protective effect Protective effects Proteins Quality of life reduce reduce COVID-19 aggravation SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 replication selected Selection single mutation single mutations specific treatment spike steroidal compounds. subversion Transgenic mouse translate transmembrane Treatment treatment of COVID-19 patients Vero Vero CCL81 cell Vero CCL81 cells viral replication Viral RNA viral variant Viral variants [DOI] 10.1080/21505594.2022.2085793 PMC 바로가기 [Article Type] Article
Acriflavine and proflavine hemisulfate as potential antivirals by targeting MproArticle Published on 2022-12-012022-11-15 Journal: Bioorganic chemistry [Category] COVID19(2023년), SARS, 치료제, [키워드] ACF acriflavine activity addition anti-SARS-CoV-2 Antiviral antiviral target BHK-21 cell Compound Coronaviruses demonstrated effective drugs effort enzymatic assay experiment HCoV-OC43 in vitro Infection inhibited inhibitor inhibitors inhibitory activity M pro M(pro) inhibitor MPro Proflavine Proflavine hemisulfate Remdesivir Replication reported SARS-CoV-2 SARS-CoV-2 epidemic SARS-CoV-2 virus SARS-CoV-2. Transcription Viral RNA [DOI] 10.1016/j.bioorg.2022.106185 PMC 바로가기
Production of single-cycle infectious SARS-CoV-2 through a trans-complemented repliconArticle Published on 2022-12-012022-11-16 Journal: Journal of medical virology [Category] COVID19(2023년), SARS, 치료기술, [키워드] acute respiratory syndrome approach BAC Cell cells clone coated Coronavirus-2 COVID-19 culture supernatant did not produce elicit expression generate IFN immune response infected cell Infection Infectious virus Live attenuated vaccine memory N protein nucleocapsid omicron overexpression plaques platform Production progeny provide Replication replicon rescued resulting RNA robust S protein SARS-CoV-2 single-cycle infectious virus. Strains transient expression transmission electron microscopy type I interferon Vaccine Viral RNA virion virus [DOI] 10.1002/jmv.28057 PMC 바로가기